Science
Martin Jinek
Molecular-biology researcher; CRISPR coauthor
Also known as M. Jinek
Who they are
Martin Jinek shares first-author credit with Krzysztof Chylinski on the 2012 programmable Cas9 paper. Its experiments showed how an engineered RNA guide could direct DNA cleavage. The work was a collaboration that also included Ines Fonfara, Michael Hauer, Jennifer Doudna and Emmanuelle Charpentier.
He contributes to the genome-editing milestone through the original experimental paper.
Selected contributions
- Shared equal-contribution first authorship of the 2012 study.Source ↗
Selected works
Academic paper · 2012 · Peer-reviewed article; author manuscript
A programmable dual RNA-guided DNA endonuclease in adaptive bacterial immunity
Jinek and colleagues explain RNA-guided Cas9 cleavage and test an engineered single guide against DNA in vitro. The paper presents programmable genome editing as a possible application, rather than an already demonstrated therapy.
Science article published online June 28, 2012; issue date August 17, 2012.
Reading scope & citation
Reuses documented prior inspection: Specific mechanism, engineered-guide, conclusion and byline passages inspected; supplementary experiments not comprehensively reviewed. Reuses the input’s documented prior inspection: Specific mechanism, engineered-guide, conclusion and byline passages inspected; supplementary experiments not comprehensively reviewed. No fresh full-work reread in this directory pass. Fresh first-page byline, equal-contribution note, affiliations, abstract and repository metadata read; earlier documented mechanism/conclusion inspection reused. Supplements not audited.
In the timeline
Documented connections
Documented · co authored with
Martin Jinek and Krzysztof Chylinski are the equal-contribution first authors of the programmable DNA-cleavage paper.
The cited paper also credits Ines Fonfara, Michael Hauer, Jennifer Doudna and Emmanuelle Charpentier. This selected pair does not exhaust the collaboration or adjudicate all priority questions.
Read the relationship record →Biography sources
- A programmable dual RNA-guided DNA endonuclease in adaptive bacterial immunity ↗Science; author manuscript hosted by UC Berkeley eScholarship